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2019
Karches, Clara H; Benmebarek, Mohamed-Reda; Schmidbauer, Moritz L; Kurzay, Mathias; Klaus, Richard; Geiger, Martina; Rataj, Felicitas; Cadilha, Bruno L; Lesch, Stefanie; Heise, Constanze; Murr, Ramona; vom Berg, Johannes; Jastroch, Martin; Lamp, Daniel; Ding, Jian; Duewell, Peter; Niederfellner, Gerhard; Sustmann, Claudio; Endres, Stefan; Klein, Christian; Kobold, Sebastian (2019).
Bispecific antibodies enable synthetic agonistic receptor-transduced T cells for tumor immunotherapy.
Clinical Cancer Research, 25(19):5890-5900.
Khosravi, Mohammad Ali; Abbasalipour, Maryam; Concordet, Jean-Paul; vom Berg, Johannes; Zeinali, Sirous; Arashkia, Arash; Azadmanesh, Kayhan; Buch, Thorsten; Karimipoor, Morteza (2019).
Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
European Journal of Pharmacology, 854:398-405.
Sparber, Florian; De Gregorio, Corinne; Steckholzer, Simone; Ferreira, Filipa M; Dolowschiak, Tamas; Ruchti, Fiorella; Kirchner, Florian R; Mertens, Sarah; Prinz, Immo; Joller, Nicole; Buch, Thorsten; Glatz, Martin; Sallusto, Federica; LeibundGut-Landmann, Salomé (2019).
The skin commensal yeast malassezia triggers a type 17 response that coordinates anti-fungal immunity and exacerbates skin inflammation.
Cell Host & Microbe, 25(3):389-403.e6.
2018
Boeck, Andreas; Landgraf‐Rauf, Katja; Vogelsang, Vanessa; Siemens, Diana; Prazeres da Costa, Olivia; Klucker, Elisabeth; von Mutius, Erika; Buch, Thorsten; Mansmann, Ulrich; Schaub, Bianca (2018).
Ca 2+ and innate immune pathways are activated and differentially expressed in childhood asthma phenotypes.
Pediatric Allergy and Immunology, 29(8):823-833.
Seehawer, Marco; Heinzmann, Florian; D’Artista, Luana; Harbig, Jule; Roux, Pierre-François; Hoenicke, Lisa; Dang, Hien; Klotz, Sabrina; Robinson, Lucas; Doré, Grégory; Rozenblum, Nir; Kang, Tae-Won; Chawla, Rishabh; Buch, Thorsten; Vucur, Mihael; Roth, Mareike; Zuber, Johannes; Luedde, Tom; Sipos, Bence; Longerich, Thomas; Heikenwälder, Mathias; Wang, Xin Wei; Bischof, Oliver; Zender, Lars (2018).
Necroptosis microenvironment directs lineage commitment in liver cancer.
Nature, 562(7725):69-75.
2017
Graf, Urs; Casanova, Elisa A; Wyck, Sarah; Dalcher, Damian; Gatti, Marco; Vollenweider, Eva; Okoniewski, Michal J; Weber, Fabienne A; Patel, Sameera S; Schmid, Marc W; Li, Jiwen; Sharif, Jafar; Wanner, Guido A; Koseki, Haruhiko; Wong, Jiemin; Pelczar, Pawel; Penengo, Lorenza; Santoro, Raffaella; Cinelli, Paolo (2017).
Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.
Nature Cell Biology, 19(7):763-773.
Hahn, M; Bürckert, J-P; Luttenberger, C A; Klebow, S; Hess, M; Al-Maarri, M; Vogt, M; Reißig, S; Hallek, M; Wienecke-Baldacchino, A; Buch, T; Muller, C P; Pallasch, C P; Wunderlich, F T; Waisman, A; Hövelmeyer, N (2017).
Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-κB signaling.
Leukemia, 32(1):72-82.
Wartewig, Tim; Kurgyis, Zsuzsanna; Keppler, Selina; Pechloff, Konstanze; Hameister, Erik; Öllinger, Rupert; Maresch, Roman; Buch, Thorsten; Steiger, Katja; Winter, Christof; Rad, Roland; Ruland, Jürgen (2017).
PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.
Nature, 552(7683):121-125.
2016
Janowski, Robert; Heinz, Gitta A; Schlundt, Andreas; Wommelsdorf, Nina; Brenner, Sven; Gruber, Andreas R; Blank, Michael; Buch, Thorsten; Buhmann, Raymund; Zavolan, Mihaela; Niessing, Dierk; Heissmeyer, Vigo; Sattler, Michael (2016).
Roquin recognizes a non-canonical hexaloop structure in the 3′-UTR of Ox40.
Nature Communications, 7:11032.
Hensel, Tim; Giorgi, Chiara; Schmidt, Oxana; Calzada-Wack, Julia; Neff, Frauke; Buch, Thorsten; Niggli, Felix K; Schäfer, Beat W; Burdach, Stefan; Richter, Günther H S (2016).
Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.
OncoTarget, 7(2):1451-1463.
Sujino, T; London, M; Hoytema van Konijnenburg, D P; Rendon, T; Buch, T; Silva, H M; Lafaille, J J; Reis, B S; Mucida, D (2016).
Tissue adaptation of regulatory and intraepithelial CD4+ T cells controls gut inflammation.
Science, 352(6293):1581-1586.
Beyer, Marc; Abdullah, Zeinab; Chemnitz, Jens M; Maisel, Daniela; Sander, Jil; Lehmann, Clara; Thabet, Yasser; Shinde, Prashant V; Schmidleithner, Lisa; Köhne, Maren; Trebicka, Jonel; Schierwagen, Robert; Hofmann, Andrea; Popov, Alexey; Lang, Karl S; Oxenius, Annette; Buch, Thorsten; Kurts, Christian; Heikenwalder, Mathias; Fätkenheuer, Gerd; Lang, Philipp A; Hartmann, Pia; Knolle, Percy A; Schultze, Joachim L (2016).
Tumor-necrosis factor impairs CD4+ T cell–mediated immunological control in chronic viral infection.
Nature Immunology, 17(5):593-603.
Nuvolone, Mario; Hermann, Mario; Sorce, Silvia; Russo, Giancarlo; Tiberi, Cinzia; Schwarz, Petra; Minikel, Eric; Sanoudou, Despina; Pelczar, Pawel; Aguzzi, Adriano (2016).
Strictly co-isogenic C57BL/6J-Prnp−/−mice: A rigorous resource for prion science.
Journal of Experimental Medicine, 213(3):313-327.
Beil-Wagner, Jane; Dössinger, Georg; Schober, Kilian; vom Berg, Johannes; Tresch, Achim; Grandl, Martina; Palle, Pushpalatha; Mair, Florian; Gerhard, Markus; Becher, Burkhard; Busch, Dirk H; Buch, Thorsten (2016).
T cell-specific inactivation of mouse CD2 by CRISPR/Cas9.
Scientific Reports, 6:21377.
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