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In the framework of a grant from the 3R (replace, reduce, refine) Competence Center of Switzerland (3RCC), we are looking for a PhD student to develop user-friendly software tools that optimize breeding strategies for laboratory rodents. These tools will incorporate various genetic, reproductive, and experimental factors to minimize the production of surplus animals while ensuring the availability of animals for research purposes.
Your project tasks:
- Design and implement algorithms to model optimal breeding termination and intermittent breeding strategies.
- Develop an online software platform that optimizes intercrosses and is accessible to scientists, breeding managers, and other stakeholders.
- Validate the software using both retrospective and prospective studies.
- Collaborate with a multidisciplinary team of experts (Cologne, Berlin, Zürich) in bioinformatics, statistics, modeling, optimization, and laboratory animal science.
- Disseminate research findings through publications and presentations.
Your profile
You should have knowledge in bioinformatics, computer science, statistics, or a related field with programming skills in e.g., Python or R. Experience with basic biological processes around breeding of animals. Passion for improving animal welfare and scientific research is a plus. You will have the opportunity to work on a cutting-edge research project with a highly collaborative team.
What we offer
We offer purposeful work to improve animal welfare based on the implementation of 3R.
The project is a collaborative undertaking between the groups of Dr. Bugnon (Zurich), Prof. Tresch (Cologne), and Prof. Brand (Berlin), which ensures superior supervision. The project is embedded in the framework of 3RCC, allowing the future student to connect to the 3R community in Switzerland and beyond.
At the Institute of Laboratory Animal Sciences (LTK), we are dedicated to performing the highest-level translational and basic research for the benefit of animals and humans alike. The place of work is the new Biomed Campus Schlieren of the University of Zurich, embedded in a vivid environment among the University of Zurich, ETH Zurich, University Hospital, Startup, and big pharma laboratories. PhD students will join a graduate program with further education offers. Participation in the UZH Bioentrepreneur education and fellowship program is a possibility when the applicant decides to commercialize the algorithms.
Start of employment
Start date is the first quarter of 2025.
Contact for further information:
Dr. Philippe Bugnon
Institute for Laboratory Animal Science
Winterthurerstrasse 190
University of Zurich
CH-8057 Zürich
+41 44 635 54 52
